A magnetically induced nano copper-catalyzed efficient and mild route for the synthesis of diaryl and alkyl/aryl sulfones from aryl/alkyl halides and tosylmethyl isocyanide (TosMIC) has been developed. A variety of aryl and alkyl sulfones have been obtained in very good to excellent yields. Sulfones containing molecules have medicinal relevance as they are known to possess various activities such as antifungal, anti-HIV, antitumor, and anticancer. Herein, a magnetically induced nano copper-catalyzed efficient and mild route for the synthesis of biaryl and alkyl/aryl sulfones from aryl/alkyl halides and tosylmethyl isocyanide (TosMIC) has been developed. A variety of aryl and alkyl sulfones have been obtained in very good to excellent yields. In this newly developed protocol TosMIC acts as sulfonyl source. The catalyst can magnetically be recovered and recycled five times without significant loss in activity.

已开发出一种磁性诱导的纳米铜催化的高效温和路线，用于从芳基/烷基卤化物和甲苯磺酰基甲基异氰化物（TosMIC）合成二芳基和烷基/芳基砜。已经以非常好的至优异的产率获得了各种芳基和烷基砜。含有砜的分子具有医学相关性，因为它们具有多种活性，例如抗真菌，抗-HIV，抗肿瘤和抗癌药。本文中，已经开发了一种磁性诱导的纳米铜催化的有效且温和的路线，用于从芳基/烷基卤化物和甲苯磺酰基甲基异氰化物（TosMIC）合成联芳基和烷基/芳基砜。已经以非常好的至优异的产率获得了各种芳基和烷基砜。在此新开发的协议中，TosMIC充当了磺酰基源。该催化剂可以磁性方式回收和再循环五次，而活性没有明显损失。