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Wound healing Activities of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine water.
Saudi Journal of Biological Sciences ( IF 4.4 ) Pub Date : 2020-05-11 , DOI: 10.1016/j.sjbs.2020.05.007
K Shanthi Kumari 1, 2 , Pabba Shivakrishna 3 , V S Ramakrishna Ganduri 1
Affiliation  

Marine species are increasingly important as a source of specific biological active metabolites. Marine species comprise almost half of global biodiversity. Oceans and sea are thus the biggest source of positive natural compounds that could be utilized in the pharmaceutical industry as functional constituents. In the present study was to find out the wound healing property of the bioactive compounds from Micrococcus sp. OUS9 isolated from marine source. The in vivo wound healing activity was studied using excision wound model. The KLUF 10 and KLUF13 ointment was prepared and used to determine wound healing activity in albino rats. Topical application of the ointment enhanced the contraction of wound in contrast with rat control group. KLUF13 had shown strong healing ability in wounds and had a positive influence on the various phases of wound repair.



中文翻译:

伤口愈合来自Micrococcus sp。的生物活性化合物的活性。从海水中分离出的OUS9。

海洋物种作为特定生物活性代谢物的来源越来越重要。海洋物种几乎占全球生物多样性的一半。因此,海洋是可在制药工业中用作功能成分的天然天然化合物的最大来源。在本研究中是要发现Micrococcus sp。的生物活性化合物的伤口愈合特性。。OUS9与海洋来源隔离。使用切除伤口模型研究体内伤口愈合活性。制备KLUF 10和KLUF13软膏,并用于确定白化病大鼠的伤口愈合活性。与大鼠对照组相比,局部应用软膏可增强伤口的收缩。KLUF13在伤口中显示出强大的愈合能力,并且对伤口修复的各个阶段均具有积极影响。

更新日期:2020-05-11
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