Naturally potential antiviral agent polysaccharide from Dendrobium nobile Lindl,Pesticide Biochemistry and Physiology

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Naturally potential antiviral agent polysaccharide from Dendrobium nobile Lindl
Pesticide Biochemistry and Physiology ( IF 4.2 ) Pub Date : 2020-05-01 , DOI: 10.1016/j.pestbp.2020.104598
Zhurui Li ₁ , Jie Xiang ₁ , Deyu Hu ₁ , Baoan Song ₁

Affiliation

A polysaccharide DNPE6(11) was purified from Dendrobium nobile Lindl. (D. nobile Lindl.). Its structural characteristic, antiviral activity, and preliminary mechanism were studied. The structural characteristic analysis indicated that DNPE6(11) was a novel homogenous heteropolysaccharide from D. nobile Lindl. Bioactivity assays indicated that DNPE6(11) possessed outstanding curative and inactivating activities against cucumber mosaic virus, which were superior to chitosan oligosaccharide and lentinan. Additionally, DNPE6(11) exhibited notable protective activity against potato virus Y, which was better than Ningnanmycin. Furthermore, the preliminary mechanism study found that DNPE6(11) cannot accumulate salicylic acid to induce systemic acquired resistance, but had a strong binding capacity for cucumber mosaic virus coat protein. Therefore, DNPE6(11) could be considered as a promising antiviral agent to study in the future.

中文翻译：

来自金钗石斛的天然潜在抗病毒剂多糖

从 Dendrobium nobile Lindl 纯化多糖 DNPE6(11)。（D. nobile Lindl。）。对其结构特征、抗病毒活性及初步作用机制进行了研究。结构特征分析表明，DNPE6(11)是一种来自金钗Lindl的新型均质杂多糖。生物活性测定表明，DNPE6(11)对黄瓜花叶病毒具有优异的治疗和灭活活性，优于壳寡糖和香菇多糖。此外，DNPE6(11)对马铃薯Y病毒表现出显着的保护活性，优于宁南霉素。此外，初步机制研究发现DNPE6(11)不能积累水杨酸诱导系统获得性抗性，但对黄瓜花叶病毒外壳蛋白具有很强的结合能力。所以，

更新日期：2020-05-01

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