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Importance of SARs-Cov-2 anosmia: From phenomenology to neurobiology.
Comprehensive Psychiatry ( IF 7.3 ) Pub Date : 2020-05-11 , DOI: 10.1016/j.comppsych.2020.152184
Stefano Pallanti 1
Affiliation  

Anosmia and hypogeusia, the inability or decreased ability to smell and taste, have been reported as common complaints in SARS-CoV-2 patients who were still in an asymptomatic phase. These impairments affect the ability to sense odors in foods and the environment, obviously affecting quality of life, related to social interactions and general well-being. The British Association of Otorhinolaryngology (ENT-UK) considers loss of sense of smell in their list of COVID-19's markers of infection. Here we present two cases in which early manifestations of anosmia and hypogeusia were experienced with psycho-sensorial and atmospheric phenomena. Psychiatrists, neurologists and physicians in general should be aware of this symptom presentation in order to avoid mistreatment, given that persistent olfactory dysfunction might increase the risks of nutritional deficit and lead to development of adjustment disorders. All clinicians should be aware that the presentation of SARS-CoV-2's symptoms goes far beyond respiratory and sensorial dimensions and involves psychosensorial and neurological dimensions; these clinical observations could shed light on the neurobiological substrates involved in COVID-19 disease.

中文翻译:

SARs-Cov-2失眠症的重要性:从现象学到神经生物学。

据报道,在仍处于无症状阶段的SARS-CoV-2患者中,常见的症状是无力和嗅觉减退,嗅觉和味觉能力下降或能力下降。这些障碍影响食物和环境中气味的感知能力,明显影响生活质量,与社交互动和总体福祉相关。英国耳鼻咽喉科协会(ENT-UK)在其COVID-19感染标志物清单中考虑了嗅觉的丧失。在这里,我们介绍了两种情况,其中伴有精神感觉和大气现象的是失眠和体力减退的早期表现。精神科医生,神经科医生和医师通常应注意这种症状,以免受到虐待,鉴于持续的嗅觉功能障碍可能会增加营养不足的风险并导致适应障碍的发展。所有临床医生都应意识到,SARS-CoV-2症状的表现远远超出呼吸和感觉方面,并且涉及心理和神经方面。这些临床观察可能会揭示与COVID-19疾病有关的神经生物学底物。
更新日期:2020-05-11
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