We present what may be the first case report of acute thrombocytopenia after tissue plasminogen activator (tPA) in the setting of stroke. Early fibrinogen degradation coagulopathy (EFDC) after tPA has been described in the past and acute thrombocytopenia may fall into this spectrum. Further studies are needed to evaluate the bleeding and mortality risk associated with thrombocytopenia after tPA.

中文翻译：

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组织中纤溶酶原激活剂后的急性血小板减少症。

我们介绍中风背景下组织纤溶酶原激活物（tPA）后急性血小板减少症的首例报道。过去已经描述了tPA后的早期纤维蛋白原降解性凝血病（EFDC），急性血小板减少症可能属于这一范围。需要进一步的研究来评估tPA后血小板减少相关的出血和死亡风险。