BACKGROUND Balance training improves postural control in Parkinson's disease (PD). However, a systematic approach for the development of individualized, optimal training programs is still lacking, as the learning dynamics of the postural control in PD, over a training program, are poorly understood. OBJECTIVES We investigated the learning dynamics of the postural control in PD, during a balance-training program, in terms of the clinical, posturographic, and novel model-based measures. METHODS Twenty patients with PD participated in a balance-training program, 3 days a week, for 6 weeks. Clinical tests assessed functional balance and mobility pre-training, mid-training, and post-training. Center-of-pressure (COP) was recorded at four time-points during the training (pre-, week 2, week 4, and post-training). COP was used to calculate the sway measures and to identify the parameters of a patient-specific postural control model, at each time-point. The posturographic and model-based measures constituted the two sets of stability- and flexibility-related measures. RESULTS Mobility- and flexibility-related measures showed a continuous improvement during the balance-training program. In particular, mobility improved at mid-training and continued to improve to the end of the training, whereas flexibility-related measures reached significance only at the end. The progression in the balance- and stability-related measures was characterized by early improvements over the first 3 to 4 weeks of training, and reached a plateau for the rest of the training. CONCLUSIONS The progression in balance and postural stability is achieved earlier and susceptible to plateau out, while mobility and flexibility continue to improve during the balance training.

中文翻译：

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帕金森病的姿势控制学习动态：稳定性稳定的早期改善，以及灵活性和活动性的持续进步。


背景平衡训练可改善帕金森病（PD）的姿势控制。然而，仍然缺乏制定个性化、最佳训练计划的系统方法，因为对训练计划中 PD 姿势控制的学习动态知之甚少。目标 我们从临床、姿势学和基于模型的新颖测量方面研究了平衡训练计划期间 PD 姿势控制的学习动态。方法 20 名 PD 患者参加平衡训练计划，每周 3 天，持续 6 周。临床测试评估训练前、训练中和训练后的功能平衡和活动能力。在训练期间的四个时间点（训练前、第 2 周、第 4 周和训练后）记录压力中心 (COP)。 COP 用于计算每个时间点的摇摆测量并确定患者特定姿势控制模型的参数。姿势测量和基于模型的测量构成了两套与稳定性和灵活性相关的测量。结果 在平衡训练计划期间，与灵活性和灵活性相关的测量结果显示出持续改善。特别是，灵活性在训练中期得到改善，并持续改善到训练结束，而灵活性相关措施只有在训练结束时才发挥作用。平衡和稳定性相关指标的进展特点是在训练的前 3 至 4 周内取得了早期改善，并在训练的其余时间达到了稳定水平。结论 平衡和姿势稳定性的进展较早实现，并且容易出现平台期，而灵活性和灵活性在平衡训练期间持续改善。