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Graphene oxide (GO) catalysed MW-assisted one-pot synthesis of densely substituted furan
Green Chemistry ( IF 9.3 ) Pub Date : 2020-05-11 , DOI: 10.1039/d0gc00723d
Anupam Jana 1, 2, 3, 4 , Nirmal Das Adhikary 1, 2, 3, 4 , Animesh Pramanik 1, 2, 3, 4
Affiliation  

Graphene oxide catalysed MW-assisted solvent-free synthetic route for the construction of densely substituted furan from simple starting materials has been reported. This green method offers a simple and highly effective strategy to synthesize a wide range of indole–furan and indole–pyrrole conjugates and bifuryl derivatives in one-pot operation. Moreover, graphene oxide, which is used for the first time in the synthesis of tetra-substituted furan, showed very high reactivity in this transformation and could be used in scalable synthesis.

中文翻译:

氧化石墨烯(GO)催化的MW辅助一锅合成重取代的呋喃

已经报道了用氧化石墨烯催化的MW辅助的无溶剂合成路线,该路线可从简单的起始原料制备稠密取代的呋喃。这种绿色方法提供了一种简单高效的策略,可以一锅操作合成大量的吲哚-呋喃和吲哚-吡咯共轭物和双呋喃衍生物。而且,在四取代呋喃的合成中首次使用的氧化石墨烯在该转化中显示出非常高的反应性,并且可以用于可扩展的合成中。
更新日期:2020-07-06
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