Ageing remarkably alters the toxicity of carbon black particles towards susceptible cells: determined by differential changes of surface oxygen groups,Environmental Science: Nano

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Ageing remarkably alters the toxicity of carbon black particles towards susceptible cells: determined by differential changes of surface oxygen groups
Environmental Science: Nano ( IF 5.8 ) Pub Date : 2020-05-11 , DOI: 10.1039/d0en00281j
Shuting Wei _{1,

2,

3,

4,

5} , Yu Qi _{5,

6,

7,

8,

9} , Li Ma _{5,

8,

10,

11,

12} , Yongchun Liu _{5,

8,

10,

11,

12} , Guangke Li _{1,

2,

3,

4,

5} , Nan Sang _{1,

2,

3,

4,

5} , Sijin Liu _{5,

6,

7,

8,

9} , Yajun Liu _{5,

8,

13,

14}

Affiliation

We uncover that O₃-induced ageing dynamically alters the surface O-functionalities of carbon black (CB) nanoparticles, a model of airborne particles. The consequent distinct bioreactivity and toxicity towards susceptible cells under low-dose exposure are largely attributed to the variant species of O-functionalities, thereby signifying the importance of the environmental ageing process in changing CB toxicity features.

中文翻译：

老化显着改变炭黑颗粒对易感细胞的毒性：取决于表面氧基团的差异性变化

我们发现，O ₃引起的老化动态地改变了炭黑（CB）纳米颗粒（一种机载颗粒的模型）的表面O-官能度。在低剂量暴露下对易感细胞产生的明显不同的生物反应性和毒性在很大程度上归因于O功能的不同种类，从而表明环境老化过程在改变CB毒性特征中的重要性。

更新日期：2020-06-18

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