A best evidence topic in thoracic surgery was written according to a structured protocol. The question addressed was: does percutaneous transthoracic needle biopsy (PTNB) increase the risk of pleural recurrence in patients with stage I lung cancer? Altogether, 298 papers were found using the reported search, of which 7 cohort studies and 1 meta-analysis represented the best evidence to answer the clinical question. The authors, journal, date and country of publication, patient group studied, study type, relevant outcomes and results of these papers were tabulated. Four cohort studies suggested an association between PTNB and pleural recurrence in patients with stage I lung cancer, while the other 3 cohort studies found that PTNB had no impact. One meta-analysis (the largest study) including 5 of the cohort studies above concluded that PTNB increased the risk of pleural recurrence among patients with stage I lung cancer with subpleural lesions. Based on the available evidence, it was suggested that there may be an association between PTNB and pleural recurrence in patients with stage I lung cancer, especially for patients with subpleural lesion.

中文翻译：

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经皮胸腔穿刺活检是否会增加I期肺癌患者胸膜复发的风险？

根据结构化协议编写了​​胸外科的最佳证据主题。解决的问题是：经皮胸腔穿刺活检（PTNB）是否增加I期肺癌患者胸膜复发的风险？通过报告检索，总共找到298篇论文，其中7项队列研究和1项荟萃分析是回答临床问题的最佳证据。将这些论文的作者，期刊，出版日期和国家，研究的患者组，研究类型，相关结果和结果制成表格。四项队列研究表明，I期肺癌患者PTNB与胸膜复发之间存在关联，而其他三项队列研究发现PTNB没有影响。一项包含上述队列研究中的5项的荟萃分析（最大的研究）得出结论，PTNB增加患有胸膜下病变的I期肺癌患者的胸膜复发风险。根据现有证据，提示I期肺癌患者，尤其是胸膜下病变患者，PTNB与胸膜复发之间可能存在关联。