Cryptochrome (CRY) photoreceptors undergo photoresponsive homo-oligomerization to become physiologically active, and BICs (blue-light inhibitors of CRYs) suppress homo-oligomerization. Structural elucidation of CRY–CRY homo-oligomers and a CRY–BIC heterodimer reveals how the activity of plant CRYs is regulated by alternative protein–protein interactions.

中文翻译：

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植物 CRY2 光激活和失活的结构视图。


隐花色素 (CRY) 光感受器经历光响应同源寡聚化，变得具有生理活性，而 BIC（CRY 蓝光抑制剂）可抑制同源寡聚化。 CRY-CRY 同源寡聚体和 CRY-BIC 异源二聚体的结构阐明揭示了植物 CRY 的活性如何通过替代蛋白质-蛋白质相互作用进行调节。