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Increasing Doses of Blueberry Polyphenols Alters Colonic Metabolism and Calcium Absorption in Ovariectomized Rats.
Molecular Nutrition & Food Research ( IF 5.2 ) Pub Date : 2020-05-27 , DOI: 10.1002/mnfr.202000031
Dennis P Cladis 1 , Hawi Debelo 2 , Pamela J Lachcik 3 , Mario G Ferruzzi 2 , Connie M Weaver 1
Affiliation  

Blueberries are rich sources of bioactive polyphenols that may provide health benefits when consumed regularly, leading to their increased marketing as dietary supplements. However, the metabolic changes associated with consuming concentrated doses of purified polyphenols, as may be present in dietary supplements, are unknown, especially when considering the colonic metabolites formed. This study aimed to evaluate the pharmacokinetics of high doses of purified blueberry polyphenols.

中文翻译:

增加蓝莓多酚的剂量会改变卵巢切除大鼠的结肠代谢和钙吸收。

蓝莓是生物活性多酚的丰富来源,经常食用可能对健康有益,从而导致其作为膳食补充剂的营销增加。然而,与食用浓缩剂量的纯化多酚(可能存在于膳食补充剂中)相关的代谢变化尚不清楚,特别是在考虑形成的结肠代谢物时。本研究旨在评估高剂量纯化蓝莓多酚的药代动力学。
更新日期:2020-05-27
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