In the current dismal situation of the COVID-19 pandemic, effective management of patients with pneumonia and acute respiratory distress syndrome is of vital importance. Due to the current lack of effective pharmacological concepts, this situation has caused interest in (re)considering historical reports on the treatment of patients with low-dose radiation therapy for pneumonia. Although these historical reports are of low-level evidence per se, hampering recommendations for decision-making in the clinical setting, they indicate effectiveness in the dose range between 0.3 and 1 Gy, similar to more recent dose concepts in the treatment of acute and chronic inflammatory/degenerative benign diseases with, e.g., a single dose per fraction of 0.5 Gy. This concise review aims to critically review the evidence for low-dose radiation treatment of COVID-19 pneumopathy and discuss whether it is worth investigating in the present clinical situation.

中文翻译：

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低剂量放射治疗COVID-19肺病的证据是什么？

在当前COVID-19大流行的令人沮丧的情况下，有效治疗肺炎和急性呼吸窘迫综合征的患者至关重要。由于当前缺乏有效的药理学概念，这种情况引起了对（重新）考虑低剂量放射治疗肺炎患者治疗的历史报道的兴趣。尽管这些历史报道本身仅是低水平的证据，但妨碍了在临床环境中进行决策的建议，但它们表明在0.3至1 Gy的剂量范围内有效，类似于近期在急性和慢性治疗中的剂量概念炎症/变性良性疾病，例如每0.5 Gy的单剂量。