Oxidative Coupling of Aldehydes with Alcohol for the Synthesis of Esters Promoted by Polystyrene-Supported N-Heterocyclic Carbene: Unraveling the Solvent Effect on the Catalyst Behavior Using NMR Relaxation.,Organic Letters

当前位置： X-MOL 学术 › Org. Lett. › 论文详情

Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)

Oxidative Coupling of Aldehydes with Alcohol for the Synthesis of Esters Promoted by Polystyrene-Supported N-Heterocyclic Carbene: Unraveling the Solvent Effect on the Catalyst Behavior Using NMR Relaxation.
Organic Letters ( IF 4.9 ) Pub Date : 2020-05-08 , DOI: 10.1021/acs.orglett.0c01188
Graziano Di Carmine ₁ , Daniele Ragno ₂ , Alessandro Massi ₂ , Carmine D'Agostino ₁

Affiliation

Heterogeneous organocatalysts hold great potential as they offer practical advantages in terms of purification and reusability compared with the homogeneous counterpart. A puzzling aspect is the solvent effect on their catalytic performance. Here we propose a new approach whereby T₁/T₂ NMR relaxation measurements are used to evaluate the strength of solvent–surface interactions in the polystyrene-supported N-heterocyclic carbene-promoted oxidation of aldehydes. The results reveal that solvents with high surface affinity lead to a decrease in catalyst activity.

中文翻译：

醛与醇的氧化偶联反应，用于合成聚苯乙烯负载的N-杂环卡宾促进的酯合成：使用NMR弛豫方法揭示溶剂对催化剂行为的影响。

非均相有机催化剂具有巨大的潜力，因为与均相对应物相比，它们在提纯和可重复使用性方面具有实用优势。令人费解的方面是溶剂对其催化性能的影响。在这里，我们提出了一种新方法，其中T ₁ / T ₂ NMR弛豫测量用于评估聚苯乙烯负载的N-杂环卡宾促进的醛氧化反应中溶剂-表面相互作用的强度。结果表明具有高表面亲和力的溶剂导致催化剂活性降低。

更新日期：2020-07-02

点击分享查看原文

点击收藏

公开下载

阅读更多本刊最新论文本刊介绍/投稿指南11