Social Safety Theory hypothesizes that developing and maintaining friendly social bonds is a fundamental organizing principle of human behavior and that threats to social safety are a critical feature of psychological stressors that increase risk for disease. Central to this formulation is the fact that the human brain and immune system are principally designed to keep the body biologically safe, which they do by continually monitoring and responding to social, physical, and microbial threats in the environment. Because situations involving social conflict, isolation, devaluation, rejection, and exclusion historically increased risk for physical injury and infection, anticipatory neural-immune reactivity to social threat was likely highly conserved. This neurocognitive and immunologic ability for humans to symbolically represent and respond to potentially dangerous social situations is ultimately critical for survival. When sustained, however, this multilevel biological threat response can increase individuals' risk for viral infections and several inflammation-related disease conditions that dominate present-day morbidity and mortality.

中文翻译：

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社会安全理论：关于生活压力、健康和行为的生物学进化观点。


社会安全理论假设，发展和维持友好的社会纽带是人类行为的基本组织原则，对社会安全的威胁是增加疾病风险的心理压力源的一个关键特征。这一表述的核心是这样一个事实：人类大脑和免疫系统主要是为了保持身体的生物学安全而设计的，它们通过不断监测和应对环境中的社会、物理和微生物威胁来实现这一点。由于历史上涉及社会冲突、孤立、贬值、拒绝和排斥的情况会增加身体受伤和感染的风险，因此对社会威胁的预期神经免疫反应可能高度保守。人类象征性地代表和应对潜在危险的社会情境的神经认知和免疫能力对于生存至关重要。然而，如果这种多层次的生物威胁反应持续下去，就会增加个体感染病毒和几种炎症相关疾病的风险，这些疾病在当今的发病率和死亡率中占主导地位。