Yeast and microalgae are microorganisms with widely diverging physiological and biotechnological properties. Accordingly, their fields of applications diverge: yeasts are primarily applied in processes related to fermentation, while microalgae are used for the production of high-value metabolites and green technologies such as carbon capture. Heterotrophic-autotrophic systems and synthetic ecology approaches have been proposed as tools to achieve stable combinations of such evolutionarily unrelated species. We describe an entirely novel synthetic ecology-based approach to evolve co-operative behaviour between winery wastewater isolates of the yeast Saccharomyces cerevisiae and microalga Chlorella sorokiniana. The data show that biomass production and mutualistic growth improved when co-evolved yeast and microalgae strains were paired together. Combinations of co-evolved strains displayed a range of phenotypes, including differences in amino acid profiles. Taken together, the results demonstrate that biotic selection pressures can lead to improved mutualistic growth phenotypes over relatively short time periods.

中文翻译：

---

在合成环境中，小球藻和酿酒酵母之间的相互关系行为演变。

酵母和微藻是具有广泛不同的生理和生物技术特性的微生物。因此，它们的应用领域各不相同：酵母主要应用于与发酵相关的过程，而微藻用于生产高价值的代谢产物和绿色技术，例如碳捕获。已经提出了异养自养系统和合成生态方法作为实现这种进化上无关的物种的稳定组合的工具。我们描述了一种全新的基于合成生态学的方法来发展酿酒酵母废水和酿酒酵母和微藻小球藻之间的合作社行为之间的合作行为。数据显示，将共同进化的酵母和微藻菌株配对在一起，可以提高生物量的产生和相互生长。共进化菌株的组合表现出一系列表型，包括氨基酸谱的差异。两者合计，结果表明，生物选择压力可以在相对较短的时间内导致改善的相互生长表型。