Poxviruses and herpesviruses encode secreted versions of cytokine receptors as a unique strategy to evade the host immune response. Recent advances in the field have shown the great impact of some of these proteins in immune modulation and viral pathogenesis, and have uncovered unique properties of these viral proteins not found in the cellular counterparts. These modifications inspired by viruses lead to improved immune modulatory activity of the soluble cytokine receptors, information that has been used to develop more efficient therapeutics to treat inflammatory conditions.

中文翻译：

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病毒编码的细胞因子和趋化因子诱饵受体。

痘病毒和疱疹病毒编码细胞因子受体的分泌形式，作为逃避宿主免疫反应的独特策略。该领域的最新进展表明，其中一些蛋白质在免疫调节和病毒发病机制中具有巨大影响，并揭示了这些病毒蛋白质在细胞对应物中未发现的独特特性。这些受病毒启发的修饰提高了可溶性细胞因子受体的免疫调节活性，这些信息已被用于开发更有效的治疗方法来治疗炎症。