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Novel 3D polymer gel dosimeters based on N-(3-Methoxypropyl)acrylamide (NMPAGAT) for quality assurance in radiation oncology
Radiation Measurements ( IF 1.6 ) Pub Date : 2020-07-01 , DOI: 10.1016/j.radmeas.2020.106372
Belal Moftah , Ahmed A. Basfar , Akram A. Almousa , Abdullah M. Al Kafi , Khalid A. Rabaeh

Abstract New anoxic and normoxic polymer gel dosimeters containing different concentrations of N-(3-Methoxypropyl) acrylamide (NMPA) are introduced in this investigation for radiotherapy treatment planning dose validation. NMPA dosimeters were irradiated to 20 Gy using the 10 MV photon beam of a medical linear accelerator under a constant dose rate. The polymerization of NMPA dosimeters occurs and increases monotonically with increasing absorbed dose. Nuclear magnetic resonance (NMR) was used to investigate the degree of polymerization of gels. The dose response in terms of spin–spin relaxation rate (R2) of NMPA dosimeters increased with the addition of glycerol. The influence of the x-ray radiation energy, dose, and dose rate, as well as the stability of the irradiated NMPA gel dosimeters were studied in order to show this preliminary study is indicative of a promising low-toxicity polymer gel dosimeter.

中文翻译:

基于 N-(3-甲氧基丙基)丙烯酰胺 (NMPAGAT) 的新型 3D 聚合物凝胶剂量计用于放射肿瘤学的质量保证

摘要 本研究介绍了含有不同浓度 N-(3-甲氧基丙基)丙烯酰胺 (NMPA) 的新型缺氧和常氧聚合物凝胶剂量计,用于放射治疗计划剂量验证。在恒定剂量率下,使用医用直线加速器的 10 MV 光子束将 NMPA 剂量计辐照至 20 Gy。NMPA 剂量计的聚合发生并随着吸收剂量的增加而单调增加。核磁共振(NMR)用于研究凝胶的聚合度。NMPA 剂量计在自旋-自旋弛豫率 (R2) 方面的剂量响应随着甘油的加入而增加。X射线辐射能量、剂量和剂量率的影响,
更新日期:2020-07-01
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