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In Celiac Disease Patients the In Vivo Challenge with the Diploid Triticum monococcum Elicits a Reduced Immune Response Compared to Hexaploid Wheat.
Molecular Nutrition & Food Research ( IF 4.5 ) Pub Date : 2020-05-18 , DOI: 10.1002/mnfr.201901032
Stefania Picascia 1 , Alessandra Camarca 2 , Monica Malamisura 3 , Roberta Mandile 3 , Martina Galatola 3 , Donatella Cielo 3 , Laura Gazza 4 , Gianfranco Mamone 2 , Salvatore Auricchio 3, 5 , Riccardo Troncone 3, 5 , Luigi Greco 3, 5 , Renata Auricchio 3, 5 , Carmen Gianfrani 1, 5
Affiliation  

Gluten from the diploid wheat Triticum monococcum (TM) has low content of immunostimulatory sequences and a high gastro‐intestinal digestibility. Gluten‐reactive T cells elicited by diploid and hexaploid (Triticum aestivum‐TA) wheat in celiac disease (CD) patients upon a brief oral challenge are analyzed.

中文翻译:

在腹腔疾病患者中,与六倍体小麦相比,用二倍体小麦的体内挑战激发了降低的免疫反应。

二倍体小麦小麦粒(TM)的面筋的免疫刺激序列含量低,肠胃消化率高。分析了二倍体和六倍体小麦Triticum aestivum ‐TA)在短暂的口服刺激下对乳糜泻(CD)患者产生的麸质反应性T细胞。
更新日期:2020-05-18
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