The purpose of the present study was to review the existing data on preoperative nonmedical factors that are predictive of outcome in brain tumor surgery. Our hypothesis was that also the individual characteristics (e.g., emotional state, cognitive status, social relationships) could influence the postoperative course in addition to clinical factors usually investigated in brain tumor surgery. PubMed, Embase, and Scopus were searched from 2008 to 2018 using terms relating to brain tumors, craniotomy, and predictors. All types of outcome were considered: clinical, cognitive, and psychological. Out of 6.288 records identified, 16 articles were selected for analysis and a qualitative synthesis of the prognostic factors was performed. The following nonmedical factors were found to be predictive of surgical outcomes: socio-demographic (age, marital status, type of insurance, gender, socio-economic status, type of hospital), cognitive (preoperative language and cognitive deficits, performance at TMT-B test), and psychological (preoperative depressive symptoms, personality traits, autonomy for daily activities, altered mental status). This review showed that nonmedical predictors of outcome exist in brain tumor surgery. Consequently, individual characteristics (e.g., emotional state, cognitive status, social relationships) can influence the postoperative course in addition to clinical factors.

中文翻译：

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脑肿瘤手术的结果预测：非医学因素影响的文献综述。

本研究的目的是回顾有关可预测脑肿瘤手术结果的术前非医学因素的现有数据。我们的假设是，除了通常在脑肿瘤手术中调查的临床因素外，个人特征（例如，情绪状态，认知状态，社会关系）也可能影响术后病程。从2008年至2018年使用与脑肿瘤，颅骨切开术和预测因子有关的术语对PubMed，Embase和Scopus进行了搜索。考虑了所有类型的结果：临床，认知和心理。在确定的6.288笔记录中，选择16篇文章进行分析，并对预后因素进行定性综合。发现以下非医学因素可预测手术结局：社会人口统计学（年龄，婚姻状况，保险类型，性别，社会经济状况，医院类型），认知（术前语言和认知缺陷，TMT-B测试表现）和心理（术前抑郁症状，人格特质，日常活动的自主权，心理状态改变）。这项审查表明，脑肿瘤手术中存在非预后因素。因此，除了临床因素外，个体特征（例如，情绪状态，认知状态，社会关系）还可以影响术后进程。这项审查表明，脑肿瘤手术中存在非医学预后指标。因此，除了临床因素外，个体特征（例如，情绪状态，认知状态，社会关系）还可以影响术后过程。这项审查表明，脑肿瘤手术中存在非预后因素。因此，除了临床因素外，个体特征（例如，情绪状态，认知状态，社会关系）还可以影响术后过程。