Kidney failure is associated with the retention and subsequent accumulation of uraemic toxins, which have detrimental effects on various physiological processes. The removal of these toxins by current dialysis modalities is inadequate, highlighting the need for innovative approaches to enhance their clearance and/or suppress their generation to improve outcomes for patients with kidney disease.

中文翻译：

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去除尿毒症毒素方法的创新。

肾衰竭与尿毒症毒素的保留和随后积累有关，尿毒症毒素对各种生理过程具有有害影响。目前的透析方式无法去除这些毒素，这突出表明需要创新的方法来提高其清除率和/或抑制其生成以改善肾病患者的预后。