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Common marmoset as a model primate for study of the motor control system.
Current Opinion in Neurobiology ( IF 4.8 ) Pub Date : 2020-05-06 , DOI: 10.1016/j.conb.2020.02.013
Masanori Matsuzaki 1 , Teppei Ebina 2
Affiliation  

The common marmoset (Callithrix jacchus), a New World monkey, is emerging as a promising animal model for biomedical and neuroscience research. This species shares its basic brain architecture, including the organization of the motor cortical areas and the connections between these and other areas, with humans and other primates. Its small and lissencephalic cerebral cortex is suitable for the application of modern biological techniques. Optogenetic stimulation of the motor cortex induces forelimb movements, and two-photon calcium imaging allows detection of forelimb movement-related activity in multiple motor cortical neurons. The common marmoset also has a large repertoire of forelimb-related behaviors and vocal communications. Thus, the common marmoset is a good model for research into voluntary forelimb movements, social behaviors, and their dysfunctions.

中文翻译:

普通mar猴作为模型灵长类动物研究电动机控制系统。

普通的mar猴(Callithrix jacchus)是一种新世界的猴子,正在成为一种有前途的生物医学和神经科学研究的动物模型。该物种共有其基本的大脑结构,包括运动皮层区域的组织以及这些区域与其他区域之间与人类和其他灵长类动物的联系。它的小脑小脑皮层适合于现代生物学技术的应用。运动皮层的光遗传学刺激诱导前肢运动,并且双光子钙成像可检测多个运动皮层神经元中与前肢运动相关的活动。普通mar猴也有大量与前肢有关的行为和声音交流。因此,普通mar猴是研究自愿前肢运动,社交行为,
更新日期:2020-05-06
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