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Genetic and environmental risk structure of internalizing psychopathology in youth.
Depression and Anxiety ( IF 4.7 ) Pub Date : 2020-05-05 , DOI: 10.1002/da.23024
John M Hettema 1, 2 , Jessica L Bourdon 1, 3 , Chelsea Sawyers 1 , Brad Verhulst 2 , Melissa A Brotman 4 , Ellen Leibenluft 4 , Daniel S Pine 4 , Roxann Roberson-Nay 1
Affiliation  

Internalizing disorders (IDs), consisting of syndromes of anxiety and depression, are common, debilitating conditions often beginning early in life. Various trait‐like psychological constructs are associated with IDs. Our prior analysis identified a tripartite model of Fear/Anxiety, Dysphoria, and Positive Affect among symptoms of anxiety and depression and the following constructs in youth: anxiety sensitivity, fearfulness, behavioral activation and inhibition, irritability, neuroticism, and extraversion. The current study sought to elucidate their overarching latent genetic and environmental risk structure.

中文翻译:

青少年内化精神病理学的遗传和环境风险结构。

由焦虑和抑郁综合征组成的内化障碍 (IDs) 是常见的、使人衰弱的疾病,通常在生命早期就开始了。各种类似特质的心理结构与 ID 相关。我们之前的分析确定了焦虑和抑郁症状之间的恐惧/焦虑、烦躁和积极影响的三方模型,以及青少年的以下结构:焦虑敏感性、恐惧、行为激活和抑制、易怒、神经质和外向性。目前的研究试图阐明它们的总体潜在遗传和环境风险结构。
更新日期:2020-05-05
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