当前位置: X-MOL 学术Microfluid. Nanofluid. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Preparation of mint oil microcapsules by microfluidics with high efficiency and controllability in release properties
Microfluidics and Nanofluidics ( IF 2.3 ) Pub Date : 2020-05-06 , DOI: 10.1007/s10404-020-02346-2
Yuhan Du , Liangji Mo , Xiaoda Wang , Hongxing Wang , Xue-hui Ge , Ting Qiu

Mint oil is a complex mixture of comparatively volatile and labile components, making it challenging to be efficiently encapsulated and retained in microcapsules using traditional approaches. Microencapsulation, by encapsulating the substance with certain shells, can effectively reduce the diffusion, evaporation and the reactions of the inside actives with the external environment. The microencapsulation of mint oil and other aromatic actives have been a prevailing method to improve the stability, prolong the storage time, and enhance the controllability of the actives. Monodisperse core–shell microcapsules based on double emulsions prepared by microfluidic technology with controllable structure, pH-responsive ability, and adjustable release properties are successfully developed. Different flow rates, glutaraldehyde concentration, solidification time and pH have been used to adjust the core sizes, the shell thickness, the crosslinking density and the shrinkage degree of the shell. By monitoring their mint oil sustained release ability through an ultraviolet spectrophotometer, appropriate conditions to form the mint oil microcapsules with high encapsulation efficiency and controllability in release properties are achieved, building the foundation for better mint oil storage, transportation, and their applications.



中文翻译:

利用微流控技术制备薄荷油微囊剂,具有高效,可控的释放性能

薄荷油是相对易挥发和不稳定成分的复杂混合物,因此使用传统方法将其有效地封装并保留在微胶囊中具有挑战性。通过将物质包裹在一定的壳中,微囊可以有效减少内部活性物质与外部环境的扩散,蒸发和反应。薄荷油和其他芳香族活性物质的微囊化是提高稳定性,延长储存时间和增强活性物质可控性的普遍方法。基于微乳液技术制备的具有双重乳液的单分散核-壳微胶囊已经成功开发,该微乳液具有可控的结构,pH响应能力和可调的释放特性。不同的流速,戊二醛浓度,固化时间和pH已用于调节核的大小,壳的厚度,交联密度和壳的收缩度。通过用紫外分光光度计监测其薄荷油的持续释放能力,可以实现形成具有高封装效率和释放性能可控性的薄荷油微胶囊的适当条件,从而为更好的薄荷油储存,运输及其应用奠定基础。

更新日期:2020-05-06
down
wechat
bug