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Sepsis-Induced Cardiomyopathy: a Comprehensive Review.
Current Cardiology Reports ( IF 3.1 ) Pub Date : 2020-05-06 , DOI: 10.1007/s11886-020-01277-2
Michael L'Heureux 1 , Michael Sternberg 2 , Lisa Brath 1 , Jeremy Turlington 3 , Markos G Kashiouris 1
Affiliation  

PURPOSE OF REVIEW To briefly review epidemiology and pathophysiology of SICM and provide a more extensive review of the data on diagnostic and management strategies. RECENT FINDINGS SICM is likely underdiagnosed and that has mortality implications. Current evidence supports speckle tracking echocardiography to identify decreased contractility irrespective of left ventricular ejection fraction for the diagnosis of SICM. There continues to be a dearth of large clinical trials evaluating the treatment of SICM and current consensus focuses on supportive measures such as vasopressors and inotropes. Sepsis is a significant cause of mortality, and sepsis-induced cardiomyopathy has both prognostic and management implications for these patients. Individualized work-up and management of these patients is crucial to improving outcomes.

中文翻译:

脓毒症诱发的心肌病:综合评价。

回顾目的 简要回顾 SICM 的流行病学和病理生理学,并对诊断和管理策略的数据进行更广泛的回顾。近期发现 SICM 可能未得到充分诊断,这对死亡率有影响。目前的证据支持散斑追踪超声心动图来识别收缩力下降,而与左心室射血分数无关,用于诊断 SICM。仍然缺乏评估 SICM 治疗的大型临床试验,目前的共识集中在支持性措施上,例如血管加压药和正性肌力药。脓毒症是导致死亡的重要原因,脓毒症引起的心肌病对这些患者具有预后和管理意义。这些患者的个体化检查和管理对于改善预后至关重要。
更新日期:2020-05-06
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