The Brazilian Journal of Infectious Diseases ( IF 3.0 ) Pub Date : 2020-05-06 , DOI: 10.1016/j.bjid.2020.04.009 Juan Li 1 , Jing Feng 1 , Tian-Hu Liu 2 , Feng-Cheng Xu 2 , Guo-Qiang Song 3
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal–oral transmission for COVID-19.
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