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Pharmacological and Therapeutic Aspects of Plants from the Genus Ferula: A Comprehensive Review.
Mini-Reviews in Medicinal Chemistry ( IF 3.3 ) Pub Date : 2020-07-31 , DOI: 10.2174/1389557520666200505125618
Mohammad Sabzehzari 1 , Mohammad Reza Naghavi 1 , Motahare Bozari 2 , Hossein M Orafai 3 , Thomas P Johnston 4 , Amirhossein Sahebkar 5
Affiliation  

Inspired by nature, humankind has been able to attain significant achievements in the drug and food industries. Particularly, medicinal plants are a rich source of medicinal, cosmetic, sanitary, and aromatic substances. Genus Ferula from the Apiaceae family is a plant genus that possesses over 170 species, which have been carefully documented with regard to their medicinal properties. Ferula spp. affects many body organs, and their respective functions, in humans, such as the immune system, gastrointestinal tract, genitourinary, endocrine, respiratory, cardiovascular, nervous system, bone (skeleton), and teeth. In spite of the benefits, ferulosis (Ferula toxicity) is an important aspect of Ferula consumption in humans and animals. Hemorrhagic problems and infertility are important signs of ferulosis. In this review, we have described all of the effects of the active ingredients of Ferula spp. and their mechanisms of actions, when known, based on an extensive literature review. Thus, our review opens a window of the benefits of Ferula as a phyto-pharmaceutical and its therapeutic applications in pharmacy, dentistry, and medicine.



中文翻译:

阿魏属植物的药理和治疗方面:全面综述。

受自然界的启发,人类已经在药物和食品工业中取得了重大成就。特别地,药用植物是药用,化妆品,卫生和芳香物质的丰富来源。pi科的Ferula属是一种植物属,拥有170多个物种,其药用特性已得到详尽的记录。Ferula spp。影响人体的许多身体器官及其各自功能,例如免疫系统,胃肠道,泌尿生殖道,内分泌,呼吸,心血管,神经系统,骨骼(骨骼)和牙齿。尽管有好处,但阿魏氏菌病(铁锈菌毒性)仍是人类和动物食用阿魏酸菌的重要方面。出血问题和不育是阿魏病的重要标志。在这篇评论中 我们已经描述了Ferula spp活性成分的所有作用。及其作用机理(已知)基于大量文献综述。因此,我们的综述打开了Ferula作为植物药的优势及其在药学,牙科和医学中的治疗应用的窗口。

更新日期:2020-08-21
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