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Effects of the intake of craft or industrial beer on serum homocysteine.
International Journal of Food Sciences and Nutrition ( IF 3.5 ) Pub Date : 2020-05-04 , DOI: 10.1080/09637486.2020.1760219
Filippo Rossi 1 , Giorgia Spigno 2 , Gloria Luzzani 2 , Maria Elisabetta Bozzoni 3 , Gianluca Donadini 1 , Jessica Rolla 4 , Terenzio Bertuzzi 1
Affiliation  

Abstract

Beer is a source of folate, vitamin B6 and B12, molecules involved in the pathways of homocysteine (HCY), a risk factor for cardiovascular disease. This research evaluated if a consumption of craft or industrial beer could reduce serum HCY. In a randomised cross-over study, 12 men (28.7 ± 6.0 years) and 12 women (29.4 ± 7.5 years), healthy, omnivorous, with normal body mass index, non-smoking and not taking oral supplements or contraceptives, followed a free-living diet and received, daily, for 3 weeks, 330 ml of industrial (4.5% of alcohol) or craft beer (9% of alcohol). Anthropometric measures and blood samples were taken at the beginning and at the end of each period. The consumption of industrial beer reduced (p < 0.05) HCY (7.35 vs. 6.50 µmol/L) and increased folic acid (3.46 vs. 3.94 ng/mL). Craft beer increased gamma-gluamyl transpeptidase (GGT) (16.6 vs. 18.6 U/L) and reduced vitamin B6 (20.9 vs. 16.9 ng/mL).



中文翻译:

摄入工艺啤酒或工业啤酒对血清高半胱氨酸的影响。

摘要

啤酒是叶酸,维生素B 6和B 12的来源,叶酸是高半胱氨酸(HCY)途径中的分子,而高半胱氨酸是心血管疾病的危险因素。这项研究评估了食用工艺啤酒或工业啤酒是否可以降低血清HCY。在一项随机交叉研究中,有12名男性(28.7±6.0岁)和12名女性(29.4±7.5岁),健康,杂食性,体重指数正常,禁烟,不服用口服补充剂或避孕药,随后免费-维持饮食,每天接受330毫升的工业饮料(酒精含量为4.5%)或精酿啤酒(酒精含量为9%),持续3周。在每个时期的开始和结束时都要进行人体测量和血液采样。工业啤酒的消耗减少(p <0.05)HCY(7.35对6.50 µmol / L)和增加的叶酸(3.46对3.94 ng / mL)。精酿啤酒增加了γ-谷氨酰转肽酶(GGT)(16.6 vs. 18.6 U / L)并降低了维生素B 6(20.9 vs. 16.9 ng / mL)。

更新日期:2020-05-04
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