Alcohol use has been associated with opioid misuse and dependence among adults with chronic pain. Yet, mechanisms underlying the relation between alcohol use problems and opioid misuse and dependence have yet to be fully explored among this population. Distress tolerance, reflecting the perceived ability to withstand negative emotional states, has demonstrated independent associations with alcohol use problems and opioid misuse, but these associations have not been explored among persons with chronic pain. The present study examined the moderating role of distress tolerance in terms of the association between alcohol use problems with opioid misuse and severity of opioid dependence. Participants included 424 adults (74.1% female; Mage = 38.3, SD = 11.1) reporting current chronic pain and opioid medication use. Results indicated that alcohol use problems were significantly associated with current opioid misuse (B = 0.54, p < .001) and severity of opioid dependence (B = 0.08, p = .002) only for those with lower distress tolerance. These findings suggest that among individuals with chronic pain, the association between alcohol use problems and opioid misuse as well as opioid dependence severity is amplified among those with lower perceived distress tolerance. (PsycInfo Database Record (c) 2020 APA, all rights reserved).

中文翻译：

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患有慢性疼痛的成年人中的酒精使用问题，阿片类药物滥用和依赖性：苦恼耐受性的作用。

在患有慢性疼痛的成年人中，酗酒与阿片类药物滥用和依赖性有关。然而，在这些人群中，酒精使用问题与阿片类药物滥用和依赖性之间关系的潜在机制尚未得到充分探索。苦恼容忍度反映了人们所感知的承受负面情绪状态的能力，已证明与饮酒问题和阿片类药物滥用存在独立的关联，但尚未在患有慢性疼痛的人中探索这些关联。本研究从与阿片类药物滥用有关的饮酒问题和阿片类药物依赖的严重性之间的关系出发，研究了遇险耐受的调节作用。参与者包括424名成人（74.1％的女性；法师= 38.3，SD = 11.1），他们报告了目前的慢性疼痛和阿片类药物的使用。结果表明，仅对于较低的苦恼耐受性者，饮酒问题与当前的阿片类药物滥用（B = 0.54，p <.001）和阿片类药物依赖性的严重程度（B = 0.08，p = .002）显着相关。这些发现表明，在患有慢性疼痛的个体中，饮酒问题与阿片类药物滥用以及阿片类药物依赖性严重程度之间的关联在知觉耐受性较低的人群中得到了增强。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。那些在较低的苦恼承受能力中的人，饮酒问题和阿片类药物滥用以及阿片类药物依赖性严重程度之间的关联被放大。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。那些具有较低感知苦难耐受性的人中，饮酒问题与阿片类药物滥用以及阿片类药物依赖程度之间的关联性被放大。（PsycInfo数据库记录（c）2020 APA，保留所有权利）。