Human respiratory syncytial virus (RSV) is the leading cause of acute bronchiolitis in infants and young children. Children under the age of 2 years, hospitalized for bronchiolitis in the pediatric clinic of a tertiary hospital in northern Greece, were tested for RSV infection during two RSV seasons (2016–2017 and 2017–2018). RSV was detected in 37 of 71 (52.1%) patients, most of them younger than 6 months. Both RSV subtypes were detected – RSV-A (54.1%) and RSV-B (45.9%) – with predominance of RSV-A during the 2016–2017 and RSV-B during the 2017–2018 season. RSV-A and RSV-B sequences clustered within the ON1 and BA genotypes, respectively. Compared to the prototype strains, several amino acid substitutions were observed in the duplication region of the G gene. The study provides a first insight into the molecular epidemiology of RSV in Greece.
Intervirology

中文翻译：

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2016-2018年希腊呼吸道合胞病毒。

人呼吸道合胞病毒（RSV）是婴幼儿急性毛细支气管炎的主要原因。在希腊北部一家三级医院的儿科诊所因支气管炎住院的2岁以下儿童在两个RSV季节（2016-2017年和2017-2018年）进行了RSV感染检测。在71例患者中有37例（52.1％）检测到RSV，其中大多数年龄小于6个月。检测到两种RSV亚型– RSV-A（54.1％）和RSV-B（45.9％）–在2016–2017年期间以RSV-A为主，在2017–2018年季节以RSV-B为主。RSV-A和RSV-B序列分别聚集在ON1和BA基因型内。与原型菌株相比，在G基因的重复区域中观察到了几个氨基酸置换。该研究提供了对希腊RSV分子流行病学的初步见解。
病毒学