Objective. Neuromodulation technologies are increasingly used for improving function after neural injury. To achieve a symbiotic relationship between device and user, the device must augment remaining function, and independently adapt to day-to-day changes in function. The goal of this study was to develop predictive control strategies to produce over-ground walking in a model of hemisection spinal cord injury (SCI) using intraspinal microstimulation (ISMS). Approach. Eight cats were anaesthetized and placed in a sling over a walkway. The residual function of a hemisection SCI was mimicked by manually moving one hind-limb through the walking cycle. ISMS targeted motor networks in the lumbosacral enlargement to activate muscles in the other, presumably ‘paralyzed’ limb, using low levels of current (<130 μ A). Four people took turns to move the ‘intact’ limb, generating four different walking styles. Two control strategies, which used ground reaction force ...

中文翻译：

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巴甫洛夫控制椎间微刺激以产生地面行走。

目的。神经调节技术越来越多地用于改善神经损伤后的功能。为了实现设备与用户之间的共生关系，设备必须增强剩余功能，并独立适应功能的日常变化。这项研究的目的是开发一种预测性控制策略，以使用脊髓内微刺激（ISMS）在半身脊髓损伤（SCI）模型中产生地面行走。方法。麻醉八只猫，并将其放在人行道上的吊索中。通过在步行周期中手动移动一只后肢来模仿半截肢SCI的残余功能。ISMS使用低电流（<130μA）瞄准腰s部肿块中的运动网络，以激活另一个可能“瘫痪”的肢体中的肌肉。四个人轮流移动“完好无损”的肢体，产生了四种不同的行走方式。两种控制策略都使用了地面反作用力...