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Characterization of a customized 3D-printed cell culture system using clear, translucent acrylate that enables optical online monitoring.
Biomedical Materials ( IF 3.9 ) Pub Date : 2020-07-19 , DOI: 10.1088/1748-605x/ab8e97
Ina Gerhild Siller 1 , Anton Enders , Pia Gellermann , Steffen Winkler , Antonina Lavrentieva , Thomas Scheper , Janina Bahnemann
Affiliation  

Cells are very sensitive to their direct environment—they place high demands, for example, on ambient culture medium, adjacent cell types, and the properties of surrounding material parts. As a result, mechanical and physical material properties—such as surface roughness, swelling, electrostatic effects, etc—can all have a significant impact on cell behaviour. In addition, a material’s composition also impacts whether that material meets biocompatibility requirements and can thus be considered for potential use in biomedical applications. The entry of high-resolution 3D printing technology in biotechnology has opened the door to individually-designed experiment-adaptable devices of almost unlimited complexity that can be manufactured within just a few hours. 3D printing materials are frequently lacking in the characteristics that make them suitable for biomedical applications, however. This study introduces a high-resolution polyacrylic 3D printing material as a potential...

中文翻译:

使用可实现光学在线监测的透明半透明丙烯酸酯对定制的 3D 打印细胞培养系统进行表征。

细胞对它们的直接环境非常敏感——它们对周围的培养基、相邻的细胞类型和周围材料部件的特性提出了很高的要求。因此,机械和物理材料特性——例如表面粗糙度、膨胀、静电效应等——都会对细胞行为产生重大影响。此外,材料的成分也会影响该材料是否满足生物相容性要求,因此可以考虑在生物医学应用中的潜在用途。高分辨率 3D 打印技术在生物技术领域的应用为个性化设计的实验适应性设备打开了大门,这些设备的复杂性几乎不受限制,可以在短短几个小时内制造出来。然而,3D 打印材料通常缺乏使其适用于生物医学应用的特性。本研究介绍了一种高分辨率聚丙烯酸 3D 打印材料作为一种潜在的...
更新日期:2020-07-20
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