Curcumin is a poly phenolic compound extracted from turmeric. Over the past years, it has acquired significant interest among researchers due to its numerous pharmacological activities like anti- cancer, anti-alzheimer, anti-diabetic, anti-bacterial, anti-inflammatory and so on. However, the clinical use of curcumin is still obstructed due to tremendously poor bioavailability, rapid metabolism, lower gastrointestinal absorption, and low permeability through cell that makes its pharmacology thrilling. These issues have led to enormous surge of investigation to develop curcumin nano formulations which can overcome these restrictive causes. The scientists all across the universe are working on designing several drug delivery systems viz. liposomes, micelles, magnetic nano carriers, etc. for curcumin and its composites which not only improve its physiochemical properties but also enhanced its therapeutic applications. The review aims to systematically examine the treasure of information about the medicinal use of curcumin. This article delivers a general idea of the current study piloted to overwhelm the complications with the bioavailability of curcumin which have exhibited an enhanced biological activity than curcumin. This article explains the latest and detailed study of curcumin and its conjugates, its phytochemistry and biological perspectives and also proved curcumin as an efficient drug candidate for the treatment of numerous diseases. Recent advancements and futuristic viewpoints are also deliberated, which shall help researchers and foster commercial translations of improved nanosized curcumin combination for the treatment of various diseases.

姜黄素是从姜黄提取的多酚化合物。在过去的几年中，由于其众多的药理活性，例如抗癌，抗老年痴呆症，抗糖尿病，抗细菌，抗炎等，它已经引起了研究人员的极大兴趣。但是，由于生物利用度极差，新陈代谢迅速，胃肠道吸收较低以及细胞渗透性低，姜黄素的临床应用仍然受到阻碍，这使其药理学令人振奋。这些问题导致开发可克服这些限制性原因的姜黄素纳米制剂的研究激增。整个宇宙的科学家都在致力于设计几种药物输送系统。脂质体，胶束，磁性纳米载体等 用于姜黄素及其复合物，不仅改善了其理化特性，而且增强了其治疗应用。这篇综述旨在系统地检查有关姜黄素的药用信息的宝藏。本文提供了当前研究的总体思路，该研究旨在克服姜黄素具有生物利用度的并发症，该并发症比姜黄素具有更高的生物活性。本文介绍了姜黄素及其缀合物的最新，详细的研究，其植物化学和生物学观点，并证明了姜黄素是治疗多种疾病的有效药物。还探讨了最新进展和未来派观点，