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Mitigating the Consequences of Subconcussive Head Injuries.
Annual Review of Biomedical Engineering ( IF 12.8 ) Pub Date : 2020-06-05 , DOI: 10.1146/annurev-bioeng-091219-053447
Eric A Nauman 1, 2, 3 , Thomas M Talavage 1, 4 , Paul S Auerbach 5
Affiliation  

Subconcussive head injury represents a pathophysiology that spans the expertise of both clinical neurology and biomechanical engineering. From both viewpoints, the terms injury and damage, presented without qualifiers, are synonymously taken to mean a tissue alteration that may be recoverable. For clinicians, concussion is evolving from a purely clinical diagnosis to one that requires objective measurement, to be achieved by biomedical engineers. Subconcussive injury is defined as subclinical pathophysiology in which underlying cellular- or tissue-level damage (here, to the brain) is not severe enough to present readily observable symptoms. Our concern is not whether an individual has a (clinically diagnosed) concussion, but rather, how much accumulative damage an individual can tolerate before they will experience long-term deficit(s) in neurological health. This concern leads us to look for the history of damage-inducing events, while evaluating multiple approaches for avoiding injury through reduction or prevention of the associated mechanically induced damage.

中文翻译:


减轻脑震荡的后果。

脑震荡性脑损伤代表了一种跨越临床神经学和生物力学工程专业知识的病理生理学。从这两个观点来看,没有限定词的术语损伤和损伤同义地表示可以恢复的组织改变。对于临床医生来说,脑震荡正在从纯粹的临床诊断演变为需要客观测量的诊断,由生物医学工程师来实现。亚脑震荡损伤被定义为亚临床病理生理学,其中潜在的细胞或组织水平的损伤(此处为大脑)不足以严重到出现容易观察到的症状。我们关心的不是一个人是否有(临床诊断的)脑震荡,而是,一个人在神经系统健康出现长期缺陷之前可以承受多少累积性损害。这种担忧促使我们寻找损伤诱发事件的历史,同时评估通过减少或预防相关机械诱发损伤来避免损伤的多种方法。

更新日期:2020-06-05
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