Georgia Gwinnett College (GGC) is an access institution with a diverse student body, located in metro Atlanta. To strengthen research skills, teach employer-valued cell biology laboratory techniques, and increase student engagement, a semester-long, inquiry-based CURE was developed and implemented in Cell Biology with Laboratory (BIOL3400K), a sophomore-level course, which serves as a “gateway” to all upper-level biology courses. This CURE centers on the investigation of a student-chosen experimental factor on the viability of cultured, mammalian cells. Through participation in this CURE, students gain experience in cell culture, fluorescence microscopy, and viability assays, and strengthen important research skills, such as literature searches, graphing, and data analyses. The impact of this CURE on student learning gains and attitudes was assessed using pre-/post-content exams and the Colorado Learning Attitudes about Science Survey (CLASS). Our data show that all students made significant content gains. Female students made larger learning gains than male students. Additionally, minority students performed better than majority students in some content areas. Student attitudes did not change, or in some cases were slightly more negative after the CURE. Overall, this CURE had a positive impact on students by engaging them in an inquiry-based laboratory experience.

中文翻译：

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一个学期很长的细胞培养和荧光显微镜CURE对一个代表性不足的STEM学生群体的学习和态度的影响†

佐治亚州格温内特学院（GGC）是位于亚特兰大都会区的一所拥有多元化学生通道的访问机构。为了加强研究技能，教授用人单位重视的细胞生物学实验室技术并增加学生的参与度，开发了一个基于学期的基于查询的CURE，并将其在大二级课程的细胞生物学与实验室（BIOL3400K）中实施，该课程用作所有高级生物学课程的“门户”。该CURE的重点是对培养的哺乳动物细胞活力进行学生选择的实验因素的研究。通过参加该CURE，学生将获得细胞培养，荧光显微镜和生存力测定的经验，并加强重要的研究技能，例如文献检索，绘图和数据分析。使用内容前/后内容测验和《科罗拉多州科学调查学习态度》（CLASS）评估了该CURE对学生学习成绩和态度的影响。我们的数据表明，所有学生在内容上都取得了显著成绩。女学生比男学生获得更大的学习收益。此外，在某些内容领域，少数族裔学生的表现优于多数族裔学生。学生的态度没有改变，或者在CURE之后有些情况下更加消极。总体而言，该CURE通过让他们参与基于调查的实验室经验而对学生产生了积极影响。在某些内容领域，少数民族学生的表现优于多数学生。学生的态度没有改变，或者在CURE之后有些情况下更加消极。总体而言，该CURE通过让他们参与基于调查的实验室经验而对学生产生了积极影响。在某些内容领域，少数民族学生的表现优于多数学生。学生的态度没有改变，或者在CURE之后有些情况下更加消极。总体而言，该CURE通过让他们参与基于调查的实验室经验而对学生产生了积极影响。