A GATE Monte Carlo model of the Philips Vereos digital photon counting PET imaging system using silicon photo-multiplier detectors was proposed. It was evaluated against experimental data in accordance with NEMA guidelines. Comparisons were performed using listmode data in order to remain independent of image reconstruction algorithms. An original line of response-based method is proposed to estimate intrinsic spatial resolution without reconstruction. Four sets of experiments were performed: (1) count rates and scatter fraction, (2) energy and timing resolutions, (3) sensitivity, and (4) intrinsic spatial resolution. Experimental and simulated data were found to be in good agreement, with overall differences lower than 10% for activity concentrations used in most standard clinical applications. Illustrative image reconstructions were provided. In conclusion, the proposed Monte Carlo model was validated and can be used for numerous studies such as optimizing acquisition parameters or reconstruction algorithms.

中文翻译：

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数字光子计数PET的蒙特卡洛模拟。

提出了使用硅光电倍增管探测器的Philips Vereos数字光子计数PET成像系统的GATE Monte Carlo模型。根据NEMA指南，根据实验数据对它进行了评估。为了保持独立于图像重建算法，使用列表模式数据进行了比较。提出了一种基于响应线的原始方法来估计固有空间分辨率而无需重建。进行了四组实验：（1）计数率和散射分数；（2）能量和定时分辨率；（3）灵敏度；以及（4）固有空间分辨率。实验和模拟数据非常吻合，对于大多数标准临床应用中使用的活性浓度而言，总体差异低于10％。提供了说明性图像重建。