Abstract

Objective: To evaluate the magnetic resonance (MR) signal intensity changes in the sacrococcygeal region of patients with uterine fibroids treated with high intensity focused ultrasound (HIFU).

Materials and Methods: Two hundred and sixty-seven patients with uterine fibroids treated with HIFU between January and December 2016 were retrospectively reviewed. All patients underwent enhanced pre- and post-HIFU MRI. Multivariate analysis was used to assess the relationship between the factors and the signal intensity changes in the sacrum and the soft tissue adjacent to the sacrum.

Results: Among the 267 patients, 122 (46%) had MR signal intensity changes in the sacrum and/or the soft tissue adjacent to the sacrum after HIFU. Multivariate analysis showed that the position of the uterus, the distance from the dorsal side of the fibroid to the sacrum, and the ablation efficiency were significantly correlated with MR signal intensity changes in the sacrum and the soft tissue adjacent to the sacrum. Further analysis showed a significant relationship between the location of the MR signal intensity changes and uterine size, the enhancement degree of the uterus. Leg pain was only seen in patients with MR signal intensity changes both in the sacrum and the soft tissue adjacent to the sacrum.

Conclusions: The location of the uterus, the distance between the dorsal side of the fibroids to the sacrum, and ablation efficiency have a significant relationship with the MR signal intensity changes. The size of the uterus and the degree of enhancement are related to the locations of MR signal changes.

摘要

目的：评估接受高强度聚焦超声（HIFU）治疗的子宫肌瘤患者cro球区的磁共振（MR）信号强度变化。

材料与方法：回顾性分析2016年1月至2016年12月接受HIFU治疗的267例子宫肌瘤患者。所有患者在HIFU MRI之前和之后均进行了增强检查。使用多变量分析来评估因素与the骨和邻近骨的软组织中信号强度变化之间的关系。

结果：在267例患者中，有122例（46％）在HIFU后在the骨和/或邻近adjacent骨的软组织中出现MR信号强度变化。多元分析表明，子宫位置，肌瘤背侧到the骨的距离以及消融效率与the骨和and骨附近软组织的MR信号强度变化显着相关。进一步的分析表明，MR信号强度改变的位置与子宫大小，子宫的增强程度之间存在显着的关系。仅在the骨和邻近adjacent骨的软组织中MR信号强度发生变化的患者中才看到腿痛。

结论：子宫的位置，肌瘤的背侧到the骨的距离以及消融效率与MR信号强度的变化有显着的关系。子宫的大小和增强程度与MR信号变化的位置有关。