Abstract

Aims

To evaluate the effects of side-alternating vibration therapy on physical function and body composition in adolescents with Down syndrome.

Methods

Fourteen adolescents (8 males) with Down syndrome (mean ± SD age: 15.5 ± 2.3 years) performed vibration treatment nine minutes daily, four times per week, for 20 weeks on a Galileo vibration platform. Data were collected at baseline and after 20 weeks of intervention. Assessments included six-minute walk test, muscle function (force plate), whole-body dual-energy X-ray absorptiometry and peripheral quantitative computed tomography of the non-dominant tibia.

Results

After 20 weeks, participants increased their distance walked in the six-minute walk test (p = 0.009), 2-leg single jump efficiency (p = 0.024) and jump velocity (p = 0.046). Participants also increased their power (p = 0.034) and reduced the time taken during the chair rise test (p < 0.001). At the total body level, increases were seen in bone mineral density (p = 0.004), bone mineral content (p = 0.043), fat free mass (p = 0.013) and lean mass (p = 0.021).

Conclusion

Side-alternating vibration therapy was associated with increases in physical function and muscle mass with no effects on bone health in adolescents with Down syndrome.

Clinical Trial Registration number

Australian New Zealand Clinical Trial Registry (ACTRN12615000092594) – registered on 4^th February 2015.

中文翻译：

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20周侧面交替振动疗法对唐氏综合症青少年的身体功能，骨骼和肌肉健康的影响。

摘要

目的

评估侧面交替振动疗法对唐氏综合症青少年身体功能和身体成分的影响。

方法

患有唐氏综合症的14名青少年（8名男性）（平均±SD年龄：15.5±2.3岁）每天在Galileo振动平台上进行九次振动治疗，每周四次，每周20次。在基线和干预20周后收集数据。评估包括六分钟步行测试，肌肉功能（测力板），全身双能X线骨密度仪和非优势胫骨的外周定量计算机断层扫描。

结果

20周后，参与者在六分钟步行测试（p  = 0.009），两腿单跳效率（p  = 0.024）和跳跃速度（p  = 0.046）中增加了步行距离。参与者还增加了力量（p  = 0.034），并减少了椅子上升测试所需的时间（p  <0.001）。在全身水平上，骨矿物质密度（p  = 0.004），骨矿物质含量（p  = 0.043），无脂肪质量（p  = 0.013）和瘦肉质量（p  = 0.021）有所增加。

结论

侧面交替振动疗法与唐氏综合症青少年的身体功能和肌肉质量增加相关，而对骨骼健康没有影响。

临床试验注册号

澳大利亚新西兰临床试验注册中心（ACTRN12615000092594）– 2015年2月4^日注册。