West Nile Virus (WNV) is a flavivirus, mosquito-borne infection and have public health importance worldwide. WNV infection have highly significant impact on animal and human health. The virus has been detected serologically in Egypt among equids. Therefore, the aim of the present study to investigate the serological situation of WNV among horse in north of Egypt and identification of WNV in vector. The serological survey was conducted on 500 serum samples that collected from horses from four governorates at north of Egypt. The infection rate was non-significant differed between four localities and the highest rate was reported in Qalyubia governorate (25.5 %) in comparison with other areas. Moreover, the WNV RNA was detected in mosquitoes and the obtained WNV sequence showed high similarity with Eg101 strain and characterized as lineage 1. The obtained findings confirm the circulation of WNV in mosquitoes and animals in Egypt.

中文翻译：

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埃及西尼罗河病毒的血清流行率和分子特征。


西尼罗河病毒 (WNV) 是一种黄病毒、蚊媒感染，对全球公共卫生具有重要意义。西尼罗河病毒感染对动物和人类健康具有重大影响。该病毒已在埃及的马科动物中通过血清学检测到。因此，本研究的目的是调查埃及北部马匹中西尼罗河病毒的血清学状况以及媒介中西尼罗病毒的鉴定。这项血清学调查是对从埃及北部四个省的马身上收集的 500 份血清样本进行的。四个地区的感染率没有显着差异，与其他地区相比，卡尤比亚省的感染率最高（25.5%）。此外，在蚊子中检测到了WNV RNA，获得的WNV序列与Eg101株具有高度相似性，并被定性为谱系1。所获得的结果证实了WNV在埃及蚊子和动物中的传播。