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Endoreplication - a means to an end in cell growth and stress response.
Current Opinion in Plant Biology ( IF 8.3 ) Pub Date : 2020-03-24 , DOI: 10.1016/j.pbi.2020.02.006
Lucas Lang 1 , Arp Schnittger 1
Affiliation  

Endoreplication, also called endoreduplication or endopolyploidization, is a cell cycle variant in which the genome is re-replicated in the absence of mitosis causing cellular polyploidization. Despite the common occurrence of endoreplication in plants and the tremendous extent in specific tissues and cell types such as the endosperm, the underlying molecular regulation and the physiological consequences have only now started to be understood. Endoreplication is often associated with cell differentiation and withdrawal from mitotic cycles. Recent studies have underlined the importance of endoreplication as a stress response and we summarize here this progress with particular focus on future perspectives offered by the recent advances in genomics and biotechnology.

中文翻译:

内复制-终止细胞生长和应激反应的一种手段。

内复制,也称为内复制或内多倍体化,是一种细胞周期变异体,其中基因组在不存在导致细胞多倍体化的有丝分裂的情况下被复制。尽管在植物中普遍发生内复制,并且在特定组织和细胞类型(例如胚乳)中存在巨大的内复制,但现在才开始了解潜在的分子调控和生理后果。内复制通常与细胞分化和退出有丝分裂周期有关。最近的研究强调了内复制作为应激反应的重要性,我们在这里总结了这一进展,特别侧重于基因组学和生物技术的最新进展所提供的未来观点。
更新日期:2020-03-24
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