Between October 2015 and March 2018, we conducted the Modified Antiretroviral Treatment Access Study (MARTAS), a nurse-delivered case management intervention to improve linkage-to-care for persons recently tested HIV positive. Adult participants from nine urban clinics in three regions of Ukraine were randomized to either MARTAS or standard of care (SOC) using individual, parallel, two-arm design. The main study outcome was linkage-to-care (defined as registration at an HIV clinic) within a 3-month period from enrollment in the study. Intention-to-treat analysis of MARTAS (n = 135) versus SOC (n = 139) showed intervention efficacy in linkage to HIV care (84.4% vs. 33.8%; adjusted RR 2.45; 95% CI 1.72, 3.47; p < 0.001). MARTAS is recommended for implementation in Ukraine and may be helpful in other countries with similar gaps in linkage-to-care. Clinicaltrials.gov registration number: NCT02338024.

2015 年 10 月至 2018 年 3 月期间，我们进行了改良抗逆转录病毒治疗可及性研究 (MARTAS)，这是一项由护士提供的病例管理干预措施，旨在改善最近检测出艾滋病毒呈阳性的人员与护理的联系。来自乌克兰三个地区的九个城市诊所的成年参与者被随机分配到 MARTAS 或标准护理 (SOC) 组，使用个体、平行、双臂设计。主要研究结果是参加研究后 3 个月内的护理联系（定义为在 HIV 诊所注册）。 MARTAS (n = 135) 与 SOC (n = 139) 的意向治疗分析显示，干预效果与 HIV 护理相关（84.4% vs. 33.8%；调整后 RR 2.45；95% CI 1.72, 3.47； p < 0.001）。建议在乌克兰实施 MARTAS，并且可能对在护理联系方面存在类似差距的其他国家有所帮助。 ClinicalTrials.gov 注册号：NCT02338024。