Cotton rats are a suitable model for the study of influenza disease symptoms and responses to influenza vaccination. We have previously shown that two immunizations with 15 µg whole inactivated virus (WIV) influenza vaccine could completely protect animals from infection with the H1N1pdm09 virus.

中文翻译：

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流感疫苗对棉花大鼠体液免疫反应和保护程度的表征：低疫苗剂量和单次接种与加强接种的影响。

棉花大鼠是研究流感疾病症状和对流感疫苗接种反应的合适模型。我们之前已经表明，使用 15 µg 全灭活病毒 (WIV) 流感疫苗进行两次免疫可以完全保护动物免受 H1N1pdm09 病毒感染。