In this study, freshwater snail (Physa acuta) was investigated to determine histopathological effects of CuSO₄ on digestive gland, foot, mantle and ovotestis under laboratory conditions. The snails were exposed to different sublethal concentrations of CuSO₄ (0.05 mg/L, 0.1 mg/L and 0.2 mg/L) periods of 10, 20 and 30 days. The relationship between CuSO₄ concentration and mortality rate in snails was calculated as Y = 8.8 + 125.14X, R² = 0.9444. The histopathological examinations revealed that CuSO₄ caused significant histopathological changes in all the tissues of the snail. The severity of these lesions in tissues increased with increasing CuSO₄ concentration and duration of exposure. The results showed that freshwater snail, Physa acuta can be considered to be a suitable bioindicator to demonstrate the toxic effect of copper in aquatic environments.

中文翻译：

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硫酸铜（CuSO4）对淡水蜗牛的影响，Physa acuta Draparnaud，1805年：组织病理学评估。

在这项研究中，对淡水蜗牛（Physa acuta）进行了研究，以确定在实验室条件下CuSO ₄对消化腺，足，地幔和卵睾丸的组织病理学影响。将蜗牛暴露于10、20和30天的不同致死浓度的CuSO ₄（0.05 mg / L，0.1 mg / L和0.2 mg / L）。计算得出蜗牛中CuSO ₄浓度与死亡率之间的关系为Y  = 8.8 + 125.14 X，R ²  = 0.9444。组织病理学检查显示CuSO ₄在蜗牛的所有组织中引起了明显的组织病理学改变。这些病变在组织中的严重程度随着CuSO ₄浓度和暴露持续时间的增加而增加。结果表明，淡水蜗牛Physa acuta被认为是证明铜在水生环境中的毒性作用的合适生物指示剂。