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Correlation of the Levels of microRNA with Cell Composition of Axillary Lymph Node in Wistar Rats with Breast Cancer
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2020-02-01 , DOI: 10.1007/s10517-020-04740-w A V Kabakov 1 , A P Lykov 1 , O V Kazakov 1 , A F Poveshchenko 1 , O V Poveshchenko 1 , I I Kim 1 , N A Bondarenko 1 , D N Strunkin 1 , A Yu Letyagin 1 , V I Konenkov 1
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2020-02-01 , DOI: 10.1007/s10517-020-04740-w A V Kabakov 1 , A P Lykov 1 , O V Kazakov 1 , A F Poveshchenko 1 , O V Poveshchenko 1 , I I Kim 1 , N A Bondarenko 1 , D N Strunkin 1 , A Yu Letyagin 1 , V I Konenkov 1
Affiliation
We studied the levels microRNA (miR-21, miR-221, miR-222, and miR-429) in blood serum, thoracic duct lymph, and breast cancer tissue, as well as the cell composition of the axillary lymph node in Wistar female rats with chemically induced breast cancer. The levels of miR-221 and miR-429 in the tumor tissue and in the lymph correlated with the decrease in lymphocyte number in the medullary cords of the axillary lymph nodes.
中文翻译：
乳腺癌Wistar大鼠腋窝淋巴结细胞组成与microRNA水平的相关性
我们研究了血清、胸导管淋巴和乳腺癌组织中 microRNA（miR-21、miR-221、miR-222 和 miR-429）的水平，以及 Wistar 女性腋窝淋巴结的细胞组成化学诱导的乳腺癌大鼠。肿瘤组织和淋巴中 miR-221 和 miR-429 的水平与腋淋巴结髓索中淋巴细胞数量的减少相关。
更新日期：2020-02-01
中文翻译：
乳腺癌Wistar大鼠腋窝淋巴结细胞组成与microRNA水平的相关性
我们研究了血清、胸导管淋巴和乳腺癌组织中 microRNA（miR-21、miR-221、miR-222 和 miR-429）的水平，以及 Wistar 女性腋窝淋巴结的细胞组成化学诱导的乳腺癌大鼠。肿瘤组织和淋巴中 miR-221 和 miR-429 的水平与腋淋巴结髓索中淋巴细胞数量的减少相关。
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