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Neural Stem/Progenitor Cells of Human Olfactory Mucosa for the Treatment of Chronic Spinal Cord Injuries
Bulletin of Experimental Biology and Medicine ( IF 0.9 ) Pub Date : 2020-02-01 , DOI: 10.1007/s10517-020-04749-1
A D Voronova 1 , O V Stepanova 1 , M P Valikhov 1 , A V Chadin 1 , A S Semkina 1 , V P Chekhonin 1
Affiliation  

We studied the efficiency of transplantation of neural stem/progenitor cells from human olfactory mucosa in chronic spinal cord injury. Neural stem/progenitor cells were obtained by a protocol modified by us and transplanted to rats with spinal post-traumatic cysts. It was shown that transplantation of neural stem/progenitor cells from human olfactory lining improved motor activity of hind limbs in the recipient rat with spinal post-traumatic cysts (according to BBB scale).

中文翻译:

用于治疗慢性脊髓损伤的人嗅觉粘膜神经干/祖细胞

我们研究了慢性脊髓损伤中人类嗅粘膜神经干/祖细胞移植的效率。神经干/祖细胞是通过我们修改的方案获得的,并移植到患有脊髓创伤后囊肿的大鼠身上。结果表明,移植来自人类嗅觉衬里的神经干/祖细胞改善了患有脊髓创伤后囊肿的受体大鼠的后肢运动活动(根据 BBB 量表)。
更新日期:2020-02-01
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