Background: Mango peel is a major by-product of mango (Mangifera Indica L.) fruit that belongs to the Anacardiaceae family. It is a tropical or subtropical fruit and is a potent source of polyphenolic contents. In traditional medicines, mango peel extract has been commonly used, either singly or in combination with other plant extracts against different ailments since ancient times.

Methods: An electronic database search for accepted articles in Pubmed, Google Scholar, Researchgate, Google, Scopus and Science Direct was used to review the scientific inputs by searching appropriate keywords. Some information was obtained from books and databases on medicinal plants used in different periods.

Results: Numerous reports revealed that mango peel contains a wide spectrum of phytochemical compounds like polyphenolics and flavonoids. A mango peel is a potential source of antioxidant, antiinflammatory, antidiabetic, antibacterial and antiproliferative properties. This review suggests that mango peel could be a potential drug to treat various clinical conditions in the future.

Conclusion: In this review, a number of phytochemicals have been summarized for their pharmacological properties and the mechanisms of action, and the possible potential therapeutic applications of mango peel against various diseases are also discussed.

背景：芒果皮是芒果（Anagifaceae）家族的主要副产品（Mangifera Indica L.）。它是热带或亚热带水果，是多酚成分的有效来源。自古以来，在传统药物中，芒果皮提取物已被普遍使用，无论是单独使用还是与其他植物提取物结合使用，均能抵抗各种疾病。

方法：使用电子数据库搜索Pubmed，Google Scholar，Researchgate，Google，Scopus和Science Direct中被接受的文章，以通过搜索适当的关键字来审查科学输入。从不同时期使用的药用植物的书籍和数据库中获得了一些信息。

结果：大量报道表明，芒果皮含有多种植物化学化合物，例如多酚和类黄酮。芒果皮是抗氧化剂，抗炎，抗糖尿病，抗菌和抗增殖特性的潜在来源。这项审查表明，芒果皮可能是将来治疗各种临床疾病的潜在药物。

结论：本综述总结了许多植物化学物质的药理特性和作用机理，并讨论了芒果皮对各种疾病的潜在治疗应用。