Introduction

Cardiovascular disease (CVD) is one of the leading causes of mortality in virally suppressed people living with HIV (PLWH) and with an aging population, is likely to become one of the leading challenges in maintaining good health outcomes in HIV infection. However, factors driving the risk of CVD in PLWH are multiple and may be different from those of the general population, raising challenges to predicting and managing CVD risk in this population.

Areas covered

In this review, we examine the relevant data regarding CVD in HIV infection including CVD prevalence, pathogenesis, and other contributing factors. We review the data regarding CVD risk prediction in PLWH and summarize factors, both general and HIV specific, that may influence CVD risk in this population. And finally, we discuss appropriate management of CVD risk in PLWH and explore potential therapeutic pathways which may mitigate CVD risk in the future in this population.

Expert opinion

Following a comprehensive review of CVD risk in PLWH, we give our opinion on the primary issues in risk prediction and management of CVD in HIV infected individuals and discuss the future direction of CVD management in this population.

中文翻译：

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HIV患者的心血管疾病：预测和管理风险的最新进展。

介绍

心血管疾病（CVD）是受到病毒抑制的HIV感染者（PLWH）和人口老龄化导致死亡的主要原因之一，它很可能成为维持HIV感染健康状况的主要挑战之一。但是，推动PLWH发生CVD风险的因素是多种多样的，并且可能与一般人群的因素不同，这给预测和管理该人群的CVD风险提出了挑战。

覆盖区域

在这篇综述中，我们检查了有关HIV感染中CVD的相关数据，包括CVD患病率，发病机理和其他影响因素。我们回顾了有关PLWH中CVD风险预测的数据，并总结了可能影响该人群CVD风险的一般因素和HIV特异性因素。最后，我们讨论了PLWH中CVD风险的适当管理，并探讨了可能减轻该人群未来CVD风险的潜在治疗途径。

专家意见

在对PLWH中CVD风险进行了全面回顾之后，我们对HIV感染者中CVD风险预测和管理中的主要问题发表了意见，并讨论了该人群中CVD管理的未来方向。