The effects of vanadium complex with enzymatic hydrolysate of soy protein (V-EHSPI) were studied in male Wistar rats with induced disorders of carbohydrate and lipid metabolism. The content of vanadium (IV) in the studied complex was 15.8 mg/g dry product. High-lipid high-carbohydrate diet was used to induce disorders of lipid and carbohydrate metabolism. Addition of vanadium in three different doses to the diet over 100-day experiment reduced body weight gain and the levels of glucose, insulin, leptin, and triglycerides. V-EHSPI produced beneficial effects on carbohydrate and lipid metabolism even in a dose 5 μg/kg body weight/day (calculated from the mean food consumption over the entire treatment period). Significant inhibition of growth and changes in the weight of organs in animals treated with V-EHSPI attested to toxicity of vanadium in the studied dose range.

中文翻译：

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钒与大豆蛋白酶解产物的复合物对雄性 Wistar 大鼠碳水化合物和脂质代谢障碍的影响

在诱导碳水化合物和脂质代谢紊乱的雄性 Wistar 大鼠中研究了钒与大豆蛋白酶水解产物 (V-EHSPI) 的复合物的影响。所研究的复合物中钒 (IV) 的含量为 15.8 mg/g 干产品。高脂高碳水化合物饮食用于诱导脂质和碳水化合物代谢紊乱。在超过 100 天的实验中，向饮食中添加三种不同剂量的钒可降低体重增加和葡萄糖、胰岛素、瘦素和甘油三酯的水平。V-EHSPI 对碳水化合物和脂质代谢产生有益影响，即使剂量为 5 μg/kg 体重/天（根据整个治疗期间的平均食物消耗量计算）。