Background 

The Geriatric Nutritional Risk Index (GNRI), based on serum albumin levels and body index, is a simple nutrition-related risk assessment instrument.

Objective 

We aimed to evaluate the prognostic value of GNRI in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention.

Methods 

We retrospectively analyzed in-hospital and long-term adverse outcomes of 786 patients with STEMI. Patients were divided into 2 groups based on their GNRI score (≤98 vs >98). Kaplan-Meier curves and Cox regression models were used to evaluate the prognostic value of the GNRI score in patients with STEMI.

Results 

Of the patients enrolled, 78 (9.9%) died of cardiovascular disease during the median follow-up period of 12.4 (8.3–15.5) months. Patients with a GNRI score of 98 or lower had a higher incidence of bleeding, cardiogenic shock, infection, acute respiratory failure, malignant dysrhythmia, atrial fibrillation, and in-hospital mortality as well as a longer length of hospital stay (P < .05). Kaplan-Meier survival analysis showed that patients with a lower GNRI score had lower cumulative survival (P < .001), regardless of age group (elderly vs middle-aged) or sex. Multivariable Cox regression analysis showed that the adjusted hazard ratio of the GNRI score for cardiovascular death was 0.934 (95% confidence interval, 0.896–0.974; P = .001).

Conclusion 

The GNRI can be used to assess prognosis of patients with STEMI and to identify those who may benefit from further nutritional assessment and intervention.

中文翻译：

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老年营养风险指数评分可预测急性 ST 段抬高心肌梗死患者的临床结果。

背景 

该老年营养风险指数（GNRI），根据血清白蛋白水平和身体指数，是一个简单的营养相关的风险评估工具。

客观的 

我们旨在评估 GNRI 对接受直接经皮冠状动脉介入治疗的 ST 段抬高型心肌梗死 (STEMI) 患者的预后价值。

方法 

我们回顾性分析了 786 名 STEMI 患者的住院和长期不良结局。患者根据 GNRI 评分分为 2 组（≤98 对 >98）。Kaplan-Meier 曲线和 Cox 回归模型用于评估 GNRI 评分对 STEMI 患者的预后价值。

结果 

在纳入的患者中，78 人 (9.9%) 在中位随访 12.4 (8.3-15.5) 个月期间死于心血管疾病。GNRI 评分为 98 或更低的患者出血、心源性休克、感染、急性呼吸衰竭、恶性心律失常、心房颤动和院内死亡率更高，住院时间更长（P < .05 ）。Kaplan-Meier 生存分析显示，无论年龄组（老年人 vs 中年）或性别，GNRI 评分较低的患者累积生存率较低 ( P < .001)。多变量 Cox 回归分析显示，GNRI 评分对心血管死亡的调整风险比为 0.934（95% 置信区间，0.896–0.974；P = .001）。

结论 

GNRI 可用于评估 STEMI 患者的预后，并确定可能受益于进一步营养评估和干预的患者。