The exact mechanisms underlying neuroinflammation and how they contribute to amyotrophic lateral sclerosis (ALS) pathogenesis remain unclear. One possibility is the secretion of neurotoxic factors, such as lipocalin‐2 (LCN2), that lead to neuronal death.

中文翻译：

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脂蛋白-2在肌萎缩性侧索硬化症中增加。

目前尚不清楚神经炎症的确切机制及其如何导致肌萎缩性侧索硬化（ALS）发病机理。一种可能性是分泌神经毒性因子，例如lipocalin-2（LCN2），可导致神经元死亡。