Childhood maltreatment has been associated to an increased risk of developing bipolar disorder (BD). A role of the hypothalamus‐pituitary‐adrenal (HPA) axis in mediating trauma‐related risk for adult psychopathology has been suggested but scarcely investigated in BD. Therefore, we explored the impact of childhood maltreatment on clinical features of BD and on the activity of the HPA axis.

中文翻译：

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成人躁郁症儿童时期虐待史的临床和神经内分泌相关性。

儿童虐待已与患躁郁症（BD）的风险增加相关。已提出下丘脑-垂体-肾上腺（HPA）轴在介导成人心理病理相关的创伤相关风险中的作用，但在BD中很少进行研究。因此，我们探讨了儿童期虐待对BD的临床特征和HPA轴活性的影响。